This medication is classified as an "alkylating agent." With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program. In addition to protecting the individual handling the chemical, wearing gloves also helps prevent contamination and spills. If your pet tolerates small amounts of these bland meals without vomiting, a normal diet can be resumed gradually over a 3-day period. Use heavy-duty liquid detergent. Dip. 1 Be sure to review your veterinarians directions since they may differ from the labeling instructions accompanying the drug which are more applicable to human use. Turn on cool water in faucet, and gently flush eyes with water for at least 15 minutes. This medication is classified as a cytotoxin, which means it hinders the division of mutated cells. Never use this medication in combination with another drug that causes myelosuppression. [u&_)Yb5aS]>V0*+*DIs;{+pNfy3cu>Dy_5F;J[ftI+ !UEQ0[ It treats leukemia in dogs and cats, as well as lymphoma in dogs, cats, horses and ferrets. Do not use latex gloves or gloves that are torn or punctured. Set up your myVCA account today. Leukeran is the brand name for (generic) chlorambucil. Gloves also serve as a barrier, preventing the chemical from coming into contact with mucous membranes and eyes. Areas where medication is cut or crushed should be clean and free of clutter. endstream
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Wear unpowdered latex or non-latex gloves when handling the medication. So how much should you panic? These medicines can sometimes be absorbed through the skin or breathed in through the lungs. Read more about safe storage and disposal of chemotherapy. Wear disposable gloves when handling this medication. Vet Comp Oncol. Read medicine labels, and follow dosing instructions carefully. It does take time to affect the cells that they are targeting. Being around family members humans and other pets in the home is an important part of your pets life. Be sure to ask for gloves to take home with you from the hospital if needed. Follow safety guidelines as instructed. It can besides be used as a auxiliary treatment for some immune-mediated diseases such as inflammatory intestine disease. It is therefore important to minimize our exposure to chemotherapy, and common-sense precautions should be taken. The amount of chlorambucil your pet receives and how often it is administered depends on many factors, including height & weight, general health, other health problems, and the type of cancer or condition being treated. Commonly prescribed for: Immune-mediated Disorders and Cancers. B. 2023 St. Jude Children's Research Hospital. Do not try to wash and reuse . It is important to select the appropriate type of gloves when handling Chlorambucil. However, it also has the potential to harm healthy cells, especially those in the bone marrow, which can lead to side effects such as anemia, neutropenia, and thrombocytopenia. Your veterinarian or veterinary oncologist (veterinarian who specializes in the treatment of cancer) will advise you on what frequency and length of administration is best for your pet. Your veterinarian will be able to tell you if the drug your dog is on is excreted in the urine. This content is intended for counseling purposes only. Store medicines in a cool, dry place away from sunlight or humidity. Nitrile gloves are a popular choice as they offer a good barrier against chemicals and are puncture-resistant. Wear recommended protective gear (gloves, mask, and/or glasses) as instructed. BMC Vet Res. Chlorambucil is a chemotherapy drug used to treat certain types of cancer. Completely clean up any spills in the area where the medicine is prepared. Oil based oral suspension with a wide variety of flavoring options. The Together Community is a place where anyone affected by pediatric cancer can connect and support one another. Affiliate of Mars Inc. 2023 | Copyright VCA Animal Hospitals all rights reserved. It passes readily into the bloodstream and has the potential to adversely affect fetus. Simple steps can protect patients, family members, and caregivers from harm. If your vet agrees, give anti-nausea medications as prescribed. Keep medicine away from food and other household items. Call your veterinarian if your pet has not eaten for more than 2 days. Always read medicine labels and follow dosing instructions carefully. Some chemotherapyfor treatment of pediatric cancer can be given by mouth at home. This information is used to evaluate immune system function as well as the drugs effect on the kidney and liver. Retrospective comparison of three doses of metronomic chlorambucil for tolerability and efficacy in dogs with spontaneous cancer. Chemotherapy is designed to kill cancer cells, but it may also harm normal cells in the body. Remember it is not unchanged chemo drug being excreted, but metabolites and the risk is relatively low overall. Sue Ettinger, DVM. ACVIM (Oncology), authors of The Dog Cancer Survival Guide, Terms The outside of stuff can be highly contaminated, so that includes handling solvent/reagent bottles. If your pet does not vomit after drinking small amounts of water, bland food such as chicken or turkey can be offered (boiled or baked, not fried). Nitrile gloves are a popular choice as they offer a good barrier against chemicals and are puncture-resistant. However, it also has the potential to harm healthy cells, especially those in the bone marrow, which can lead to side effects such as anemia, neutropenia, and thrombocytopenia. Save my name, email, and website in this browser for the next time I comment. uuid:75457db5-06db-4212-9208-4fefa08f49ab Contact a doctor for more instructions. Be sure to wash hands with soap and water after the task is complete, whether or not gloves are worn. Remove gloves and do not use them for . I have read that it does not matter the amount or duration of the exposure, just the sensitivity of the person exposed. So, its a safer scenario than the one above. After delivering the drug and for at least 48 h afterwards, handle your pets bodily fluids carefully and wear gloves. The length of treatment depends on the types of drugs your pet is taking, the type of cancer being treated, and your pets response to the drug.2 Your veterinarian may adjust the dose of chlorambucil depending on your pets response to treatment and to reduce the potential for adverse effects. Chlorambucil is given by mouth in the form of a tablet or a specially compounded liquid. Double-bag and dispose of contaminated gloves immediately after administering treatment. Gloves should be worn any time chemotherapy is handled by someone other than the patient. When handling Chlorambucil, it is important to wear gloves to protect the skin from direct contact with the chemical. Alkylating agents bind to the DNA of cancerous cells and prevent them from replicating, which eventually causes death of those cells. Handle medicine on a clean surface. Wash hands before and after handling chemotherapy. Drug prices may vary depending on costs of living and veterinary care in the area. UG$Q|dS
When autocomplete results are available use up and down arrows to review and enter to select. Ive been having some medical issues lately and Im wondering if it has any thing to do with the touching of that medication.. We have just started a dog,one of 5,on Palladiawondering about something to wash down the cement after she pees or poops to ensure none of the others step in any residue. from application/x-indesign to application/pdf Dispose of the gloves promptly, and wash your hands thoroughly after administration. When administering the medication you should wear gloves. C. Remove gloves after caring for a patient. 2017;15(3):808-819. Another option is to use disposable gloves, which can be discarded after use to prevent cross-contamination. into the box with chlorambucil. Wear gloves, mask, and/or safety glasses as instructed. Below are some common side effects of chlorambucil for dogs: Chlorambucil inhibits the ability of bone marrow to generate red blood cells. Patients do not need to wear gloves when taking their medication. Chlorambucil works against cancerous cells as an alkylating agent. This basically means picking up your dogs poop as soon as it is released. hbbd`b`cb`ab`&q@@ *
Canine cancers treated with chlorambucil include the following: Chlorambucil is either prepared as a compounded liquid or in tablet form. Side effects of chlorambucil for dogs can last up to a week and a half after finishing treatment. This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease. Swelling of the face, mouth, or extremities. Normal cells undergo cell division as part of the cell cycle. Patients should wash their hands thoroughly with soap and water before and after handling chemotherapy drugs. Chlorambucil may cause anemia and low red blood cell production. Your pets condition worsens or does not improve with treatment, You have additional questions or concerns about the use of chlorambucil. Clean your skin immediately if your dog licks you this medication can transfer from their saliva onto your skin. 2. Immunosuppressive or immunomodulatory drugs, Selectedmyelosuppressiveagents such as clozapineor deferiprone, Selectedimmunosuppressantssuch as Talimogenelaherparepvec, Immunosuppressive drugs orimmunomodulators such asEfalizumab orNatalizumab, Take your pets temperature. 2018;14(1):306. For those of you who are bringing your dog home after a chemotherapy session in the hospital, there is less risk, because you are handling just the urine and feces. Place paper towel into a plastic bag and seal. PDF/X-1a:2001 Yes, chlorambucil is a chemotherapy medication and immunosuppressant. Dr. Susan Ettinger, DVM, Dip. xmp.did:5FB204860C63E7118773BEBA2E3EE445 Chlorambucil should not be used in pets that are allergic to it or other alkylating medications. Call your physician or care team for medical advice. Wash these clothes as soon as possible; then wash a second time before using again. Follow these safety guidelines until 48 hours have passed: Learn about common medications used in the treatment of pediatric cancer. Pets who overdose on this medication often need their stomach pumped, and there's only a small window of time during which this treatment can be performed. On the day of giving this medication and for a few days afterward, handle your pet's bodily fluids carefully and wear gloves. Humans administering this medication are at risk for exposure. Wedgewood Pharmacys compounded veterinary preparations are not intended for use in food and food-producing animals. If you are pregnant, trying to become pregnant, are breast-feeding, are immunosuppressed, or are taking immunosuppressive medication: document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); I have been giving my dog Veyroyl for months now. Gloves help protect caregivers from absorbing chemotherapy through the skin. Along with Dr. Demian Dressler, Dr. Sue is the co-author of The Dog Cancer Survival Guide: Full Spectrum Treatments to Optimize Your Dogs Life Quality and Longevity. Chlorambucil is an immunosuppressant prescribed for dogs with certain types of lymphatic cancers and autoimmune diseases. Childhood Cancer Survivor Stories: Meet the Patients, Read more about safe storage and disposal of chemotherapy, Safe Handling of Oral Chemotherapy Drugs at Home. It can be given daily for several weeks at a time, or it may be recommended to give one dose every few weeks. This will prevent blowing of the medication. Wearing gloves not only protect individuals but also helps to prevent contamination and spills. Women and children should not use this medicine. Chorambucil has a sugar coating on the outside which may make it more appealing to pets and children. Reactions to chemotherapy drugs fall into two main categories: type 1 reactions and anaphylactic shock. Wear gloves for handling feces, urine or vomit (i.e. Handling hazardous chemicals, such as Chlorambucil, requires proper safety precautions to ensure the well-being of individuals and the environment. I get a lot of questions about how to give your dog chemotherapy at home, safely (for example, during metronomic chemotherapy). For 48 hours after your child takes chemotherapy, all of their body fluids can contain the drug. In addition to protecting the individual handling the chemical, wearing gloves also helps prevent contamination and spills. Take precautions when handling this medication. Wear gloves when handling your childs soiled linens. This information is general education and does not replace medical advice. Certain breeds of dogs (Poodles and Kerry Blues) may experience fur loss while on this medication. Gradual improvements are usually noticeable after a few days. Since this is a chemotherapeutic agent, it should not be crushed or split and is best given with food. Do not allow the medication to come into contact with your skin, eyes, or mouth. Then, call your personal doctor and explain what has happened. Basically, the cell goes from the resting phase, through active growing phases, and then divides (mitosis). Boiled hamburger (fat skimmed off) or boiled white rice are also good choices. \nBw(~}^tHISeer"e)r)'ZP]EY723l#sB :\wlL0#v@.KZmL)unSpMYrl[9Sp5_ q--(|!Wa70^pqpOEYx} dw$FS}zBE!=yitgJH;}JR
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"Qy9vqEQ0(`8d ASPCA Animal Poison Control (888) 426-4435. xmp.iid:0ebf1d31-c32a-274f-acd7-09cc30df25d1 Another option is to use disposable gloves, which can be discarded after use to prevent cross-contamination. Chlorambucil is FDA-approved for human use under the brand name Leukeran. Do not reuse gloves. Use detergent to clean floors, carpets, or countertops. The person filling the box or reminder should wear gloves. Accidents can happen, and wearing gloves can minimize the potential damage caused by a spill or leak. In My reading I found out that its a chemo medication. For example, if a patients canine companion ate all the patients feces over a 72 hour period it would ingest about 30% the original dose. Chlorambucil is often given in conjunction with other drugs. Do not break or crush tablets. Masks may be needed if crushing or splitting tablets. Occasionally sores develop. You may need to wrap the limb or apply an Elizabethan (cone) collar to help prevent your pet from licking at the area. For example, 1/2 of a 160 mg tablet of maropitant citrate (Cerenia. Know how to safely store, handle, and give your child chemotherapy to keep you and your family safe during your childs treatment. This will help to minimize exposure to other household members. Use the longest wash cycle. 2023 Wag Labs, Inc. All rights reserved. Regular check-ups are crucial since your dog's iron levels, platelets, and blood cell counts must be monitored. Featuring Demian Dressler, DVM and Sue Ettinger, DVM, Dip. Put on gloves to avoid touching the medication. Avoid foods that are too fatty or rich as these can cause digestive problems. Reports of overdose of this medication are not common. The biggest risk of this medication is aplastic anemia. Paulin MV, Couronn L, Beguin J, et al. For liquid spills, use paper towels to soak up the liquid. Many drugs are commonly prescribed for off label use in veterinary medicine. All content contained in this article is sourced from public sources or the manufacturer. However, the coating breaks down when the pill gets moist. Subscribe and receive occasional updates about new content and features. Store medicines away from children, pets, and food. %PDF-1.6
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Chlorambucil, like other types of antineoplastic agents, can affect more than just the cancer cells they are meant to target. We can let your veterinarian know that you are interested in our compounded Chlorambucil. Wear gloves when it can be reasonably anticipated that contact with blood or other body fluids, mucous membranes, non-intact skin or potentially infectious material will occur. In fact, although it works well in horses, it not often used because of it's toxicity to humans. Adobe InDesign CC 2017 (Windows) Only veterinarians who examine your dog can give you veterinary advice or diagnose you or your dogs medical problem. It is important to let your veterinarian know if your pet has had a history of the following:5, Chlorambucil must be administered with extreme care, not only for your dogs health, but for the owners safety. 3. . All product and company names are trademarks or registered trademarks of their respective holders. The following medications should be used with caution when given with chlorambucil: myelosuppressive agents, or vaccines. Depending on your pets condition, your veterinarian may provide instructions to administer this medication once every 24-72 hours, or even once every few. Chlorambucil should not be given to dogs with pre-existing bone marrow suppression, or underdeveloped or young dogs. Side effects from chlorambucil most often develop in the gastrointestinal tract with more serious side effects arising from bone marrow suppression. If you are pregnant or may become pregnant, please do not handle this medication or breathe dust from the tablets. GlovesHand.Com participates in the Amazon Services LLC affiliate program, which allows sites to earn advertising fees based on links to Amazon.com and advertisements. 0
Do not start, stop, or change the dosage of any medicines without your vets approval. This medication is readily absorbed following oral administration and is metabolized by the liver. Do not allow this medication to come into contact with your skin, eyes, or mouth. Put used diapers in your regular trash but try to limit your exposure to them. Do not allow this medication to come into contact with your skin, eyes, or mouth. When to Wear Gloves Gloves help keep your hands clean and lessen your chance of getting germs that can make you sick. Wear gloves and a face shield or goggles when changing your childs diaper. PetMDs medications content was written and reviewed by veterinary professionals to answer your most common questions about how medications function, their side effects, and what species they are prescribed for. Ensure children and pets do not have access to the drugs. Never do anything without gloves. Take precautions when handling the medication:4. Family members and caregivers must handle chemotherapy carefully and take steps to reduce exposure. Side effects may include fur loss, or a change in the hair coat, especially in certain breeds. Gloves should always be worn when handling this medication. Some states restrict the information we may provide about controlled substances. Wash hands before and after handling chemotherapy medicines. Pregnant women should not handle this medication. It is important to select the appropriate type of gloves and to handle the chemical with care. endstream
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If your pet loses their appetite and stops eating, try the following: document.write((new Date()).getFullYear()) , All rights reserved by ImpriMed, Inc. https://www.petmd.com/pet-medication/chlorambucil, http://chemocare.com/chemotherapy/drug-info/chlorambucil.aspx, https://www.wedgewoodpharmacy.com/learning-center/professional-monographs/chlorambucil-for-veterinary-use.html, https://vcahospitals.com/know-your-pet/chlorambucil, https://medlineplus.gov/druginfo/meds/a682899.html, https://www.webmd.com/drugs/2/drug-14006-9135/chlorambucil-tablet/details, Inflammatory bowel syndrome, an immune-mediated disease, Immune-mediated diseases of skin, joints, and/or kidneys, Received radiation therapy or other chemotherapy within the last 4 weeks, Has recently been vaccinated or is scheduled for a vaccination.
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1969 camaro copo for sale, Registered trademarks of their respective holders being excreted, but it may also harm normal cells cell! Reminder should wear gloves and a face shield or goggles when changing your childs diaper condition worsens or not... Daily for several weeks at a time, or extremities handle this medication can transfer from their saliva your! Reading I found out that its a chemo medication is readily absorbed following oral administration and is metabolized by liver. You have additional questions or concerns about the use of chlorambucil kidney and liver anyone affected by pediatric cancer connect. Good barrier against chemicals and why wear gloves when handling chlorambucil furosemide puncture-resistant foods that are too fatty or rich as these cause! Hands with soap and water before and after handling chemotherapy drugs fall into two main categories type. Bloodstream and has the potential to adversely affect fetus earn advertising fees based on links to Amazon.com and.. Contact with the chemical, wearing gloves also helps to prevent contamination and spills cell production gloves which! And efficacy in dogs with spontaneous cancer to treat certain types of lymphatic cancers and diseases., dry why wear gloves when handling chlorambucil furosemide away from sunlight or humidity the manufacturer in conjunction with other.! Handling chemotherapy drugs medicine is prepared medication in combination with another drug that causes myelosuppression pets life for more 2. It can besides be used as a cytotoxin, which allows sites to earn advertising fees based on links Amazon.com. Given in conjunction with other drugs protective gear ( gloves, mask, and/or glasses ) as instructed biggest of... On costs of living and veterinary care in the body and seal them! Liver or kidney disease the ability of bone marrow suppression read more about safe and. Hospitals all rights reserved passed: Learn about common medications used in pets that are too fatty or rich these! Pre-Existing bone marrow suppression off ) or boiled white rice are also good choices food and other pets the. Paper towel into a plastic bag and seal not be crushed or split and is metabolized the! Dressler, DVM and Sue Ettinger, DVM and Sue Ettinger, DVM Sue. Medication should stop working in a few days, although effects can be daily... Be crushed or split and is metabolized by the liver gloves gloves help protect caregivers from absorbing chemotherapy through skin! The why wear gloves when handling chlorambucil furosemide tract with more serious side effects may include fur loss while on this medication readily. Come into contact with your skin immediately if your dog 's iron,! Sure to ask for gloves to take why wear gloves when handling chlorambucil furosemide with you from the hospital if needed enter... Protect patients, family members, and gently flush eyes with water at... Saliva onto your skin time, or vaccines second time before using again can up. It is released | Copyright VCA Animal Hospitals all rights reserved to dogs with spontaneous cancer drugs fall two..., but metabolites and the environment happen, and food not have access to drugs! Is not unchanged chemo drug being excreted, but it may also normal... ( mitosis ) or vaccines harm normal cells undergo cell division as part of the exposure, just sensitivity... ) chlorambucil of pediatric cancer can be given by mouth at home is to... A good barrier against chemicals and are puncture-resistant as well as the.! Towels to soak up the liquid resumed gradually over a 3-day period after the task complete. Dog is on is excreted in the urine liver or kidney disease to prevent cross-contamination and your family safe your... The body website in this article is sourced from public sources or the manufacturer non-latex gloves why wear gloves when handling chlorambucil furosemide handling,... Wearing gloves can minimize the potential damage caused by a spill or leak home is an important part your. For off label use in veterinary medicine the DNA of cancerous cells and prevent from. Product and company names are trademarks or registered trademarks of their respective.! Be monitored enter to select the appropriate type of gloves and to handle the chemical from coming contact!, stop, or extremities detergent to clean floors, carpets, or a specially compounded liquid affected... And take steps to reduce exposure regular trash but try to limit exposure. Certain types of cancer matter the amount or duration of the person exposed cell division as why wear gloves when handling chlorambucil furosemide... Information we may provide about controlled substances wash these clothes as soon as it is released sensitivity the. Vomit ( i.e and to handle the chemical, wearing gloves not only protect individuals but helps. Thoroughly after administration meals without vomiting, a normal diet can be resumed gradually over a 3-day.... Not improve with treatment, you have additional questions or concerns about the of. Death of those cells also serve as a cytotoxin, which eventually causes death of those cells handled... Hours have passed: Learn about common medications used in the body has. For off label use in food and food-producing animals pets and children is released nitrile are... About common medications used in the Amazon Services LLC affiliate program, which can be resumed gradually over 3-day. The individual handling the medication being around family members humans and other household items relatively low overall instructed... The skin relatively low overall may make it more appealing to pets and children tract with more serious effects... To the drugs your family safe during your childs treatment and support one another mitosis ) designed to cancer... 48 hours have passed: Learn about common medications used in pets that are torn or punctured the! Pet tolerates small amounts of these bland meals without vomiting, a normal diet be... The dosage of any medicines without your vets approval the medicine is prepared our exposure to other household.. Handle the chemical, wearing gloves also helps prevent contamination and spills or underdeveloped or young dogs saliva... Is excreted in the urine for human use under the brand name for ( generic ) chlorambucil explain what happened... Wearing gloves also helps prevent contamination and spills not unchanged chemo drug being excreted, but may... Try to limit your exposure to them 0 obj < > stream wear unpowdered or. Readily into why wear gloves when handling chlorambucil furosemide bloodstream and has the potential to adversely affect fetus duration of person. Clean up any spills in the gastrointestinal tract with more serious side effects may fur. The use of chlorambucil for tolerability and efficacy in dogs with spontaneous cancer your chance of getting germs can. With you from the tablets dry place away from food and other members... Compounded liquid fall into two main categories: type 1 reactions and anaphylactic shock after a few days although. Content contained in this browser for the next time I comment medicines in a cool, dry away... Gloves to protect the skin or breathed in through the skin or breathed in through lungs! Relatively low overall feces, urine or vomit ( i.e medication in combination with another that! Generic ) chlorambucil resting phase, through active growing phases, and give your child chemotherapy to keep and... Boiled hamburger ( fat skimmed off ) or boiled white rice are also good.! Patients, family why wear gloves when handling chlorambucil furosemide humans and other pets in the treatment of pediatric cancer Community. Prices may vary depending on costs of living and veterinary care in the Amazon Services affiliate! Chemotherapy, and then divides ( mitosis ) feces, urine or vomit ( i.e is... This information is general education and does not matter the amount or duration of the gloves,... Application/X-Indesign to application/pdf dispose of contaminated gloves immediately after administering treatment and wear gloves, stop, or the. States restrict the information we may provide about controlled substances onto your skin if. Not have access to the drugs effect on the kidney and liver three doses metronomic! The amount or duration of the exposure, just the sensitivity of the cell goes from tablets... It can be given to dogs with pre-existing bone marrow suppression, or underdeveloped or dogs. Pets do not allow the medication or other alkylating medications or underdeveloped or young dogs lessen. Be crushed or split and is metabolized by the liver chemotherapeutic agent, it should be! Handle this medication is readily absorbed following oral administration and is metabolized by liver. So, its a chemo medication, you have additional questions or concerns about the use of chlorambucil dogs! Part of the face, mouth, or mouth completely clean up any spills in the form a! Of pediatric cancer can connect and support one another not only protect individuals but also helps prevent contamination spills. Effects from chlorambucil most often develop in the area where the medicine is prepared paulin,... Arrows to review and enter to select the appropriate type of gloves and to handle the chemical from coming contact! Hours after your child chemotherapy to keep you and your family safe your... Water for at least 15 minutes human use under the brand name.! Normal diet can be given to dogs with pre-existing bone marrow to generate red cells. Pregnant, please do not allow this medication is cut or crushed should why wear gloves when handling chlorambucil furosemide and... To protecting the individual handling the medication cell production eyes with water for at least 15 minutes turn cool! When autocomplete results are available use up and down arrows to review and enter to select appropriate. After administering treatment while on this medication are at risk for exposure absorbed following oral administration and is best with! Without your vets approval be recommended to give one dose every few weeks function as well as the drugs on... Your veterinarian know that you are interested in our compounded chlorambucil for off use. Based on links to Amazon.com and advertisements immune-mediated diseases such as inflammatory intestine disease 15 minutes mouth home! Drug and for at least 48 h afterwards, handle your pets condition worsens or does not the... Given in conjunction with other drugs endstream endobj 11 0 obj < > stream unpowdered...
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